Anna Ouyang Moench has been appointed as the new showrunner for the second season of the Amazon Prime Video series Mr. and Mrs. Smith. Moench steps into the role following the departure of co-creator Francesca Sloane, who left the series in September 2025 to pursue an overall deal at HBO, including work on the third season of Big Little Lies.

Production for Season 2 was initially scheduled to begin in the fall but has since been postponed indefinitely. Mark Eydelshteyn and Sophie Thatcher are set to lead the cast for the upcoming season.

Moench brings extensive experience from her recent work as a writer and supervising producer on the acclaimed Apple TV series Severance. She also serves as an executive producer on the second season of Beef at Netflix and is developing several original projects. In addition to her television work, Moench is an accomplished playwright, with her latest production, Your Local Theater Presents: A Christmas Carol, by Charles Dickens, Again, enjoying a sold-out run at La Jolla Playhouse in 2024.

Peter Friedlander, global head of television for Amazon MGM Studios, commented, “Anna is a phenomenal storyteller with an incredible ability to balance character-driven drama, sharp humor, and emotional depth. Her work on Beef and Severance speaks for itself, and we’re thrilled to have her at the helm of Mr. and Mrs. Smith Season Two as she builds on the series’ compelling world and pushes it into exciting new territory for our global Prime Video customers.”

Moench is represented by WME, Heroes & Villains, and Jackoway Austen.

Mr. and Mrs. Smith was co-created by Francesca Sloane and Donald Glover. Glover starred in the first season alongside Maya Erskine, with a notable guest cast including Michaela Cole, John Turturro, Alexander Skarsgård, Sarah Paulson, and Parker Posey. None of these actors are currently expected to return for the second season.

The series earned 16 Emmy nominations for its debut season, including best drama series, best actor in a drama (Glover), and best actress in a drama (Erskine). It won two Emmys: best stunt coordination for a drama and best guest actress in a drama (Cole).

Mr. and Mrs. Smith is a reimagining of the 2005 film starring Brad Pitt and Angelina Jolie. The series follows two strangers who are recruited by a mysterious spy agency, offering them a life of espionage, luxury, and a dream home in Manhattan. The twist: they must assume new identities as a married couple, John and Jane Smith, and navigate both weekly high-stakes missions and the complexities of their arranged relationship.

Donald Glover and Francesca Sloane continue as executive producers, joined by Arnon Milchan, Yariv Milchan, Natalie Lehmann, Michael Schaefer, Stephen Glover, Anthony Katagas, and Fam Udeorji. The series is co-produced by New Regency and Amazon MGM Studios.

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